{"product_id":"thinking-like-a-phage-the-genius-of-the-viruses-that-infect-bacteria-and-archaea-9780990494317","title":"Thinking Like a Phage: The Genius of the Viruses That Infect Bacteria and Archaea","description":"\u003cp\u003eIt isn't easy to be a phage. First, what is a phage? A phage is a virus that infects Bacteria. To succeed, a phage must encounter, recognize, and enter a particular type of bacterial cell, then coerce it to make more phages rather than more cells. Of course, the cell resists this hostile takeover in numerous ways, all of which the successful phage overcomes. The triumphant phage then proceeds with its replicative business. In this engaging book, Merry Youle relates some of the tactics used by 21 pheatured phages to outwit their host and successfully maintain their own lineage generation after generation.\u003c\/p\u003e\u003cp\u003eThis ongoing contest of wits is a matter of life and death for both players. A phage chromosome arriving in its intended host cell is met by the cell's state-of-the-art defenses. Unless it dodges or neutralizes every one, it will be chopped into a nutritious snack for the cell. If the phage survives, it then quickly diverts the cell's machinery to production of more phages, rather than more cells. Under skillful phage supervision, manufacture of phage components proceeds at top speed, with all parts produced when needed and in the quantities required. As the pieces come off the assembly line, they self-assemble into sophisticated transport packages, each carrying a phage chromosome and capable of delivering it into a new host cell. When a new crop of progeny is ready - perhaps 25, 100, or more of them - the phage ruptures the cell to free them all and send them out into the world in quest of hosts of their own. Overall, a balance is maintained so that both the phages and their hosts thrive.\u003c\/p\u003e\u003cp\u003eMany phages have the option to instead follow a different script. When they arrive in a host, they can opt to delay immediate hostile takeover and to instead form a coalition with the host for mutual benefit. In this case, as the cell grows and divides, the phage is replicated and inherited by both daughter cells. This can continue for many generations. However, if the cell encounters life-threatening difficulties, the phage ends the alliance and switches to rapid replication. Cell rupture and release of the new generation follows quickly.\u003c\/p\u003e\u003cp\u003eEach step of the way presents challenges that test the ingenuity of the phages. In this book, tales of phage prowess are accompanied by pertinent electron micrographs; every chapter is enlivened by informative illustrations created by San Diego fine artist Leah Pant a. The writing focuses on strategies and underlying principles, with a minimum of jargon. Since some knowledge of molecular biology is required to appreciate phage wizardry, a primer of the needed basics is provided for those unfamiliar with that subject. Thus, these phage adventures can be enjoyed by a wide audience.\u003c\/p\u003e\u003cp\u003eDespite being the most abundant life form, the phages - being much smaller than even the microbes they infect - elude our everyday perception. \u003cem\u003eThinking Like a Phage\u003c\/em\u003e offers a tour of this unseen dimension of life on Earth. Whether you are an expert or new to the phage world, these vignettes drawn from phage life will intrigue you. Awareness of this vast, creative, yet invisible realm can enrich your appreciation for the living world of which we, as \u003cem\u003eHomo sapiens\u003c\/em\u003e, are only a small part.\u003c\/p\u003e\u003cbr\u003e\u003cbr\u003e\u003cb\u003eAuthor:\u003c\/b\u003e \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=AUTH-5279585\"\u003eMerry Youle\u003c\/a\u003e\u003cbr\u003e\u003cb\u003ePublisher:\u003c\/b\u003e Wholon\u003cbr\u003e\u003cb\u003ePublished:\u003c\/b\u003e 05\/01\/2017\u003cbr\u003e\u003cb\u003ePages:\u003c\/b\u003e 310\u003cbr\u003e\u003cb\u003eBinding Type:\u003c\/b\u003e Paperback\u003cbr\u003e\u003cb\u003eWeight:\u003c\/b\u003e 1.23lbs\u003cbr\u003e\u003cb\u003eSize:\u003c\/b\u003e 9.00h x 6.00w x 0.84d\u003cbr\u003e\u003cb\u003eISBN13:\u003c\/b\u003e 9780990494317\u003cbr\u003e\u003cb\u003eISBN10:\u003c\/b\u003e 0990494314\u003cbr\u003e\u003cb\u003eBISAC Categories:\u003c\/b\u003e\u003cbr\u003e- \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=CAT-SCI\"\u003eScience\u003c\/a\u003e | \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=BISAC-SCI045000\"\u003eLife Sciences | Microbiology\u003c\/a\u003e\u003cbr\u003e- \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=CAT-SCI\"\u003eScience\u003c\/a\u003e | \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=BISAC-SCI099000\"\u003eLife Sciences | Virology\u003c\/a\u003e\u003cbr\u003e- \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=CAT-SCI\"\u003eScience\u003c\/a\u003e | \u003ca href=\"https:\/\/sureshotbooks-com.myshopify.com\/search?type=product%2Carticle%2Cpage\u0026amp;q=BISAC-SCI049000\"\u003eLife Sciences | Molecular Biology\u003c\/a\u003e\u003cbr\u003e\u003cp\u003e\u003ci\u003eThis title is not returnable\u003c\/i\u003e\u003cbr\u003e\u003c\/p\u003e","brand":"Wholon","offers":[{"title":"Default Title","offer_id":44486032621805,"sku":"9780990494317","price":42.67,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0550\/8097\/6621\/products\/img_28cc0eff-6892-48ad-8991-30903d1c545b.jpg?v=1700811713","url":"https:\/\/sureshotbooks.com\/products\/thinking-like-a-phage-the-genius-of-the-viruses-that-infect-bacteria-and-archaea-9780990494317","provider":"SureShot Books Publishing LLC","version":"1.0","type":"link"}