Transdermal Patch of Lamivudine and Stavudine-Loaded Ethosomes

TDDS are the ideal delivery system for drug that undergo hepatic first pass metabolism. Lamivudine and Stavudune drug was successfully designed and developed by trial and error method. Formulations were prepared by employing combination of HPMCK15M, PVPK30, and EC in various ratios. From the evaluation results it was conclude that TF5 show highest release at 12 hrs. with suitable polymer ratio and penetration enhancer and it was observed that Higuchi kinetics model most suitable kinetic model for drug release from all patches.

Author: Shailesh Gupta, Ravikant Gupta, Alok Pail Jain
Publisher: LAP Lambert Academic Publishing
Published: 04/27/2020
Pages: 56
Binding Type: Paperback
Weight: 0.21lbs
Size: 9.00h x 6.00w x 0.13d
ISBN13: 9786200788641
ISBN10: 6200788642
BISAC Categories:
- Medical | Pharmacology

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