Tamoxifen: Pioneering Medicine in Breast Cancer


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Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens.- Tamoxifen Goes Forward Alone.- Metabolites of Tamoxifen as the Basis of Drug Development.- Adjuvant Therapy - The Breakthrough.- The Wisconsin Story in the 1980's: Discovery of Target Site Specific Estrogen Action.- Carcinogenesis and Tamoxifen.- Chemoprevention: Cinderella waiting for the ball.- Tamoxifen and Raloxifene head to head: The STAR TRIAL.- Acquired resistance to Tamoxifen: back to the beginning.- The legacy of Tamoxifen.- Appendix: Four decades of discovery in breast cancer research and treatment - an interview with V. Craig Jordan by Marc Poirot.- Selected Awards that Recognize the Contribution of Tamoxifen and Raloxifene to Medicine.



Author: Philipp Y. Maximov, Russell E. McDaniel, V. Craig Jordan
Publisher: Springer
Published: 08/06/2013
Pages: 199
Binding Type: Hardcover
Weight: 1.05lbs
Size: 9.20h x 6.40w x 0.70d
ISBN13: 9783034806633
ISBN10: 3034806639
BISAC Categories:
- Medical | Endocrinology & Metabolism
- Medical | Oncology | General
- Medical | Pharmacology